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09:00 - 09:30
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Welcome Coffee
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| 09:30 - 10:05 |
Keynote: Xiadong Zhang, The Francis Crick Institute, United Kingdom
Structures and mechanisms of RAD51 modulators |
| 10:05 - 10:30 |
Pauline Dupaigne, Institut Gustave Roussy, France
Molecular and Structural Insights into RAD51 and RAD52 at stalled
Replication Forks
|
| 10:30 - 10:45 |
Short talk: Frédéric Baudat, Institut of Human Genetics, France
The FIGNL1-FIRRM complex prevents massive DNA damage-
independent loading of RAD51 and DMC1 and is required
to complete meiotic recombination in mouse
|
| 10:45 - 11:00 |
Short talk: Hajar Saidi, CEA, France
A new mouse mutant reveals a specific role of
RPA-MEIOB-SPATA22 in the dynamics of RAD51-associated
meiotic recombination intermediates
|
| 11:00 - 11:30 |
Coffee break |
| 11:30 - 11:55 |
Wolf Heyer, University of California, USA
Structures and functions of yeast Rad51 paralog complexes |
| 11:55 - 12:10 |
Short talk: Françoise Ochsenbein, I2BC, France
From Disorder to Assembly: The Rad52 C-Terminus as an
Assembly Chaperone for Rad51 Filaments
|
| 12:10 - 12:25 |
Short talk: Patryk Ludzia, University of Cambridge, UK
Structural and biochemical characterization of BRCA2-dependant
loading of RAD51 filaments
|
| 12:25 - 12:35 |
Sponsors presentation: SFC, ARC, Université Paris Saclay
and Université Paris Cité
|
| 12:30 - 14:30 |
Lunch and poster session #1 |
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Session 3
|
| 14:30 - 15:05 |
Maria Jasin, Sloan-Kettering Institute, USA
Complex roles for BRCA2 during meiosis
|
| 15:05 - 15:30 |
Roland Kanaar, Erasmus MC, The Netherlands
Dual posttranslational BRCA2 modification drives RAD51
nucleoprotein filament assembly |
| 15:30 - 15:45 |
Short talk: James Haber, Brandeis University, USA
Comparisons of Dmc1- and Rad51-mediated meiotic recombination
|
| 15:45 - 16:00 |
Short talk: Sophie Zinn-Justin, I2BC, France
The meiotic recombinogenic filament: a platform for binding to
intrinsically disordered regions of proteins
|
| 16:00 - 16:30 |
Coffee break |
| 16:30 - 16:55 |
Kara Bernstein, University of Pennsylvania, USA
RAD51D promotes RAD51 filament formation by
regulating BCDX2 ATPase activity |
| 16:55 - 17:10 |
Short talk: Irena Draskovic, Institut Curie, France
Homologous recombination goes live: Endogenous tagging
of human RAD51 reveals the dynamic behavior of RAD51 filaments
|
| 17:10 - 17:25 |
Short talk: Alex Zelensky, Erasmus MC, Netherlands
Live Cell Imaging of Mouse RAD51
|
| 19:30 |
Dinner at « Le Barbezingue » |